These were a gift to a missionary friend. She received them also thinking they would be great teaching tools. I never opened a package. As yet my friend has given no feed back but if they do have God Bless You on each tissue it could be a down beat. As for roughness...a lot of bulk tissues are not soft.
I did not realize that each tissue was stamped with "God Bless You" until I offered one to a friend. She could not blow her nose on a tissue that said that. I offered them to two other friends who responded the same way. They all agreed they would have loved them if the words were only on the package and not the individual tissues. And the tissues were not very soft.