This is the best book I have read so far that explains that it's not really about the fat; it's about the inflammation (and how to get rid of it). Using the metaphor "The Perfect Nutritional Storm," Sears guides us through the history of how cheap food became available in the USA: not the good fruits and vegetables, but rather the cheap omega-6 fats and high glycemic carb foods. He points specifically to three factors that have created this health disaster in the USA. The nice thing about Dr. Sears' books is that you don't have to read the previous ones to understand the material because he always has nice summaries of his prior discoveries---so this book includes info on not only the inflammation issue, but also the Zone diet and fish oil. If you've ever been envious of someone who can eat all they want and not gain weight, you won't be after reading this book. It's not only the overweight who are susceptible to toxic problems. And an overweight person can even be healthy. Sears claims that the heaviest man in the world went on this diet and lost 400 pounds (at the time of the writing) and even long before reaching his ideal weight, achieved very ideal blood chemistry. Sears takes us on a tour of the hormones of hunger. You will better understand the delicate balance of what causes hunger when you read this.