1. One of the reasons for the increasing emergence of antibiotic-resistant bacteria is the use of antibiotics when they are not indicated. Has this ever affected your doctor’s treatment decision? How did you react?
2. Do you believe that most researchers are ethical? Why or why not? Does this affect your confidence in medications your doctor prescribes?
3. Were you able to form a mental picture of John Ramsey’s late wife, Beth? How would you characterize her? Do you think her advice to him was good?
4. Picture yourself as Sara Miles, forced to work closely with a man who has hurt you deeply. Could you maintain a professional relationship, or would your history color your actions? What if he held the only key to your patient’s survival?
5. Did your concept of Rip Pearson change as the story progressed? Was there a point when you didn’t trust him? What about Mark Wilcox?
6. What qualities did you find in Jack Ingersoll? What about Carter Resnick? What did you think their driving force was?
7. Contrast Sara’s feelings toward Chelsea Ferguson and Randall Moore. What factors influenced her attitude?
8. Rip was faced with suggesting a treatment that would save a patient’s life but might have late consequences that would be life changing and possibly fatal. Assume the patient was unable to make a decision and no family was available. What would you do?
9. Do you believe God should have punished Jack for his deeds? What do you think is the basis for bad things happening to people?
10. What did you take away from this novel? How will it affect the way you live your own life?